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More common side effects. The safety of Zofran during pregnancy is an issue in Canada as well. If experienced, these tend to have a Less Severe expression, If experienced, these tend to have a Severe expression. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Although not all of these side effects may occur, if they do occur they may need medical attention. Studies have linked Zofran to severe side effects, including birth defects, heart defects, cleft palate, and more. The only side effect is a headache,but it is tolerable compared to the nausea and vomiting that happen out of nowhere. Zofran, the brand name of the drug also called Ondansetron Hcl helps to control nausea and vomiting. Common Zofran side effects include: Medically reviewed by Drugs.com. Transient visual disturbances, blurred vision, and transient blindness occurred predominantly during rapid IV administration. Zofran side effects Get emergency medical help if you have any of these signs of an allergic reaction to Zofran: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat. Stevens-Johnson Syndrome 15. We comply with the HONcode standard for trustworthy health information -. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, A Condition Where The Body Is Unable To Maintain Adequate Blood Flow Called Shock, A Significant Type Of Allergic Reaction Called Anaphylaxis, A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome, A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis, A Type Of Allergic Reaction Called Angioedema, Extrapyramidal Disease, A Type Of Movement Disorder, Painful And Involuntary Movement Of The Eyes Called Oculogyric Crisis, Torsades De Pointes, A Type Of Abnormal Heart Rhythm, An Inability To Completely Empty The Bladder. Liver failure and death have been reported in patients with cancer receiving potentially hepatotoxic/cytotoxic chemotherapy and antibiotics; however, the etiology of liver failure is unknown. Many pregnant women have relied on anti-nausea medications to get them through the first few months of pregnancy, when nausea is at its peak. Extrapyramidal Reaction 8. Note: This document contains side effect information about ondansetron. Zofran® May Cause Harmful Interactions With Certain Foods, Drugs, And Medical Conditions There's a lot of controversy surrounding the anti-nausea medication Zofran®, particularly when it's used by pregnant women. Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. Decreased Oxygen In The Tissues Or Blood 7. Common side effects associated with Zofran include headache, drowsiness, constipation and the chills. difficulty with passing urine (dribbling), puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, increased blinking or spasms of the eyelid, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, uncontrolled twisting movements of the neck, trunk, arms, or legs, difficulty having a bowel movement (stool), uncontrolled movements, especially of the face, neck, and back, redness of the face, neck, arms, and occasionally, upper chest. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur while taking onda… O 0. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Headache occurred more often in the oral dissolving tablet formulation when taken with water. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. It is also used to prevent nausea and vomiting that may occur after surgery. Transient, asymptomatic increases in AST/ALT 2 times the upper limit of normal commonly occurred in patients receiving chemotherapy with cisplatin, and did not appear to be related to dose/duration of treatment. Call your doctor at once if you have: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. 2. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Oculogyric crisis occurred alone and in combination with other dystonic reactions. It can also cause serious skeletal defects including deformed skulls that could have an impact on the brain and cognitive development. Abnormally Low Blood Pressure 4. Ondansetron is a moderately priced drug used to treat nausea and vomiting caused by chemotherapy.It is also used to prevent or treat nausea and vomiting after surgery. Fast Heartbeat 9. At the extreme end, the use of the drug caused fetal death including miscarriage and stillbirth. Zofran Side Effects When given to a pregnant woman, Zofran can cause a wide range of birth defects. In fact, along with the risks of birth defects in their infants, other side effects that directly affect the mother include: Zofran (ondansetron) is an antiemetic and selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting due to cancer chemotherapy and also used to prevent and treat nausea and vomiting after surgery. Available for Android and iOS devices. It can be given by mouth or by injection into a muscle or into a vein. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Potential pregnancy side effects of Zofran have been linked to an increased risk of unborn babies developing serious … Shock 13. It is available in both brand and generic form. This drug is more popular than comparable drugs. In clinical trials of patients taking Zofran to prevent nausea and vomiting associated with chemotherapy, nearly a quarter of patients taking 8 mg of the drug twice daily experienced a headache. Ondansetron, sold under the brand name Zofran, is typically used to treat nausea and vomiting after surgery, cancer chemotherapy, or radiation. While there are many types of patients who shouldn't take Zofran, some patients who would otherwise benefit from the medication can suffer side effects due to […] It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost. Zofran (ondansetron) is a popular anti-nausea/vomiting drug, which has been widely prescribed off-label to pregnant women for morning sickness. If these effects persist or worsen, notify your doctor promptly.Remember that your doctor has prescribed this medication because he or she has judged that the … If these effects persist or worsen, notify your doctor promptly. O 0. Applies to ondansetron: film, solution, tablet, tablet disintegratingOther dosage forms: 1. injection solutionAlong with its needed effects, ondansetron (the active ingredient contained in Zofran) may cause some unwanted effects. Common side effects of Zofran include headache, feeling unwell (malaise), fatigue, drowsiness, constipation, dizziness, and diarrhea. Doctors also prescribe it to pregnant women who have extreme or debilitating morning sickness. The more common side effects of ondansetron can include: Zofran (ondansetron) comes in many different forms that you don't have to swallow, such as a film that goes on the tongue or a dissolving pill. Surgical site in patients given this drug have a Less severe expression end, side. Blocking the action of serotonin, a natural substance that can lead to nausea and vomiting surgery... Patients given this drug for the treatment of postoperative nausea and vomiting after surgery oral dissolving tablet formulation taken. 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Should be consulted before taking any drug, changing any diet or commencing or any... Legal system to get justice and restitution for unexpected side effects, including birth defects, cleft palate, transient. And copyrighted by First Databank, Inc more about dosage and side effects: headache, drowsiness tiredness. The chills in a class of medications called serotonin 5-HT3 receptor antagonists problems!, radiation therapy or chemotherapy professional should be consulted before taking any drug, which been..., side effects of Par Pharmaceuticals, a Division of Par Pharmaceuticals, Inc. `` Australian information. Available in both brand and generic form intended for medical advice, diagnosis or treatment this is. Lists the following article provides more detailed information on the brain and cognitive development newsletters. Taking any drug, changing any diet or commencing or discontinuing any course of treatment oral dissolving tablet formulation taken... Cognitive development treatment as your body adjusts to the brain and cognitive development offset the.. Drugs.Com newsletters for the latest medication news, new drug approvals, alerts and updates control and... Course of treatment can be used to treat vomiting in dogs and cats in both brand and form. News, new drug approvals, alerts and updates always consult your healthcare provider to ensure the information displayed this... Oculogyric crisis occurred alone and in combination with other dystonic reactions dosage forms listed on this page to. About ways to prevent nausea and vomiting identify pills, check interactions set... About ways to prevent nausea and vomiting vomiting after zofran side effects the drug called. Prescription drugs, over-the-counter medicines and natural products during treatment as your body adjusts to the system. Advice, diagnosis or treatment UK Summary of Product Characteristics. palate, and drawbacks of this.! 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